VII, diabetes etiology

1, with type 1 diabetes-related factors are:
Their immune system defects: Because patients with type 1 diabetes in the blood can be found a variety of autoimmune antibodies, such as glutamic acid decarboxylase antibody (GAD antibodies), islet cell antibody (ICA antibodies) and so on. These abnormal antibodies can damage the body's own insulin secretion of insulin B cells, so that should not normally secrete insulin.
Genetic factors: Genetic defects prompted the current study is the incidence of type 1 diabetes foundation, the performance of such genetic defects in the human sixth chromosome abnormalities on HLA antigen. Prompted scientists: I have diabetes onset familial characteristics - If your parents have diabetes, then a person with no family history compared to, you more susceptible to the disease.
HIV infection may be an incentive: you may be surprised, many scientists suspect that the virus also can cause I diabetes mellitus. This is because I diabetes patients over a period of time before the virus infection too often, and I-type diabetes "epidemic", often occur in the virus after the pandemic. Viruses, such as those that cause mumps and rubella virus can cause polio and Coxsackie virus family, can play a role I diabetes mellitus.
Other factors: such as milk, oxygen free radicals, some drugs, such as rodent control, whether these factors can lead to diabetes, scientists are studying.
2, with type 2 diabetes-related factors
Genetic factors: type 1 diabetes and is similar to type 2 diabetes also have the characteristics of familial incidence. It is very likely that the relevant genetic and gene. Such genetic characteristics of type 2 diabetes than type 1 diabetes more obvious. For example: one of the twins suffering from type 1 diabetes, another has 40% chance of suffering from the disease; but if it is type 2 diabetes, while another 70 percent will have the opportunity to suffer from type 2 diabetes.
Obesity: type 2 diabetes may be an important factor in obesity. Genetic causes can lead to obesity, the same can also be caused by type 2 diabetes. Obese patients with body-centered excess fat on the abdomen, they are fat than those who concentrated in the buttocks and thighs are more prone to type 2 diabetes.
Age: Age is also a type 2 diabetes risk factors. Half of patients with type 2 diabetes after the age of onset in 55. Elderly patients are also prone to diabetes and older people tend to overloading.
Modern lifestyle: eat high-calorie food and exercise can also cause the reduction of diabetes, some people think this is caused due to obesity. Obesity and type 2 diabetes as in those who have been eating habits and activities of "Westernization" of Asian and Latin American businessmen in the United States become more popular.
3, diabetes and pregnancy-related factors
Hormone: pregnancy when the placenta will produce a wide range of fetal growth for growth hormones, these hormones on the healthy growth of the fetus is very important, but it can block the body's insulin-mother role, so trigger diabetes. 妊娠 Article 24 of pregnancy thoughtful 28 cycle is a peak of these hormones during pregnancy diabetes is often time-fat.
Genetic basis: the occurrence of gestational diabetes mellitus in patients with type 2 diabetes if there is a considerable risk (but with type 1 diabetes has nothing to do). Some people think, therefore causing gene with gestational diabetes cause of type 2 diabetes genes may be related to each other.
Obesity: Obesity is not only easily lead to type 2 diabetes, the same can also be caused by gestational diabetes mellitus.